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Bible Verses About Despair

“For I said in my haste, I am cut off from before thine eyes: nevertheless thou heardest the voice of my supplications when I cried unto thee.”

— Psalms 31:22

Psalm 88 is the Bible's despair psalm — it ends in darkness and was still kept in the hymnbook. That is the pattern these verses follow: despair is spoken aloud to God, never swallowed silently. The fifteen verses below are the Bible's direct address to that situation, shown in full KJV text from Psalms 31:22 to Matthew 11:28.

Quick answer: The best-known verse about despair here is Psalms 31:22: "For I said in my haste, I am cut off from before thine eyes: nevertheless thou heardest the voice of my supplications when I cried unto thee." Psalms 69:1 follows close behind: "Save me, O God; for the waters are come in unto my soul." Both are public-domain translations, shown in full on the cards below with a modern-English toggle.

The 15 verses, in full text

01 · King James Version

For I said in my haste, I am cut off from before thine eyes: nevertheless thou heardest the voice of my supplications when I cried unto thee.

Psalms 31:22

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02 · King James Version

Save me, O God; for the waters are come in unto my soul.

Psalms 69:1

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03 · King James Version

I cried unto God with my voice, even unto God with my voice; and he gave ear unto me.

Psalms 77:1

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04 · King James Version

O LORD God of my salvation, I have cried day and night before thee:

Psalms 88:1

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05 · King James Version

Hear my prayer, O LORD, and let my cry come unto thee.

Psalms 102:1

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06 · King James Version

Hear me speedily, O LORD: my spirit faileth: hide not thy face from me, lest I be like unto them that go down into the pit.

Psalms 143:7

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07 · King James Version

How long wilt thou forget me, O LORD? for ever? how long wilt thou hide thy face from me?

Psalms 13:1

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08 · King James Version

O my God, my soul is cast down within me: therefore will I remember thee from the land of Jordan, and of the Hermonites, from the hill Mizar.

Psalms 42:6

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09 · King James Version

Why art thou cast down, O my soul? and why art thou disquieted within me? hope thou in God: for I shall yet praise him, who is the health of my countenance, and my God.

Psalms 42:11

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10 · King James Version

Why sayest thou, O Jacob, and speakest, O Israel, My way is hid from the LORD, and my judgment is passed over from my God?

Isaiah 40:27

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11 · King James Version

My soul hath them still in remembrance, and is humbled in me.

Lamentations 3:20

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12 · King James Version

And said, I cried by reason of mine affliction unto the LORD, and he heard me; out of the belly of hell cried I, and thou heardest my voice.

Jonah 2:2

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13 · King James Version

For we would not, brethren, have you ignorant of our trouble which came to us in Asia, that we were pressed out of measure, above strength, insomuch that we despaired even of life:

2 Corinthians 1:8

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14 · King James Version

The spirit of a man will sustain his infirmity; but a wounded spirit who can bear?

Proverbs 18:14

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15 · King James Version

Come unto me, all ye that labour and are heavy laden, and I will give you rest.

Matthew 11:28

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When to read these verses

These verses are for the hard hours — the waiting room, the graveside, the first week, the anniversary nobody else remembers. They are short on explanation and long on presence, which matches what actually helps. Read them aloud if you can; comfort verses were written for voices, not screens.

How to use this list

Each verse card carries the King James text with a World English Bible toggle for modern phrasing — worth checking before reading aloud at a service or sending to someone who finds the old grammar hard. Copy the verse; it keeps.

Frequently Asked Questions

What is the best Bible verse about despair?
Psalms 31:22 is the one most readers land on: "For I said in my haste, I am cut off from before thine eyes: nevertheless thou heardest the voice of my supplications when I cried unto thee." Psalms 69:1 is the usual second: "Save me, O God; for the waters are come in unto my soul." The full list of fifteen is on this page — there is no single required verse, and different seasons call for different texts.
Can these verses be read at a service or sent to someone grieving?
Yes — that is a primary use. Every verse on this page is public domain in both translations shown (King James Version and World English Bible), so they can be printed, read aloud, or included in a card without permission. The copy button renders the verse with its reference, ready to paste.
Where in the Bible does it talk about despair?
The verses on this page come from 7 books of the Bible — most notably Psalms, Isaiah, Lamentations and 4 more — spanning both Old and New Testaments. The distribution itself is worth noticing: Scripture addresses despair in more than one voice, which is why the page shows whole verses rather than a single proof text.
How do I use a list of verses about despair?
Read the list once slowly, then keep the one verse that fits your situation close — the copy button places it wherever you will actually see it. Every card can be switched to the World English Bible for modern wording, and the random verse tool at the top of the page can draw one verse from this theme at a time if the whole list is more than today needs.

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